ZO Skin Health Peptide Facial Refining Concentrate is an advanced peptide serum clinically shown to deliver a more sculpted appearance and refined facial geometry in just 12 weeks. Powered by four next-generation peptide technologies, this innovative formula visibly lifts, smooths, and restores volume for youthful-looking definition. Ideal as a complement to injectable treatments or as a powerful standalone solution for daily use. Features and Benefits: Targets Wrinkles & Volume Loss – Helps reduce the look of expression and static wrinkles while restoring volume for a more lifted, refined appearance. Complements Injectable Treatments – Enhances and extends the visible effects of neurotoxins and dermal fillers. Supports Skin Structure – Strengthens the appearance of skin’s structural integrity while boosting natural hyaluronic acid for plumper, more hydrated skin. Soothes & Protects – ZO’s exclusive ZPOLY™ complex helps reduce redness and supports the skin barrier. Clinically Proven Results Wrinkle Reduction – 92% of participants saw fewer visible fine lines. Volume & Firmness – 86% experienced improvement in hollow areas and 84% noticed more defined facial geometry. Skin Elasticity – Improvements in firmness and elasticity were seen as early as 2 weeks, with continued results at 12 weeks. Hydration – 100% of subjects experienced improved skin hydration by week 4. Key Ingredients Acetyl Octapeptide-3 – A neuropeptide that softens the look of dynamic lines, especially around the eyes and forehead. Acetyl Hexapeptide-8 – Works synergistically to smooth deeper static wrinkles and support natural collagen. Volumizing Tripeptide – Boosts natural hyaluronic acid for fuller, plumper-looking skin. Refining Peptide Complex – A dual-peptide blend that enhances skin structure for a sculpted, lifted appearance. Alcohol-Free and Fragrance-Free

Product Form Serum Gel For Skin Types Acne Prone Skin Sensitive Skin Pigmented Skin Normal Skin Mature Skin Oily Skin Congested Skin Combination Skin Dry Skin All Skin Types Application Area(s) Face Treatments Neck Treatments

ZO Skin Health Peptide Facial Refining Concentrate Wrinkle Modulating + Plumping Serum

Name: ZO Skin Health Peptide Facial Refining Concentrate Wrinkle Modulating + Plumping Serum
Brand: ZO Skin Health
SKU: ZO-054
Price: 265.00 USD
Availability: InStock

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$265.00

Shipping calculated at checkout.

Refines facial geometry
Lifts, defines facial contours and smoothes
Reduces redness and supports skin barrier

Size:

1 fl oz

Product only available for Rejuvent Skincare VIP+.

You must have a Rejuvent Skincare VIP+ account to purchase it. Please fill out an order request to order.

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Dr. Bomer’s Insight

Kelly Bomer, MD

“It is a clear gel that goes on clean and provides plumping and lift to the skin. Using it twice a day, I have noticed that my skin feels plumper smoother and is more reflective. I think this is a great product for anybody looking for plumping and tightening of the skin. It is good for all skin types.”
-Dr. Kelly Bomer

The New Science of Sculpting

Product Overview

ZO Skin Health Peptide Facial Refining Concentrate is an advanced peptide serum clinically shown to deliver a more sculpted appearance and refined facial geometry in just 12 weeks. Powered by four next-generation peptide technologies, this innovative formula visibly lifts, smooths, and restores volume for youthful-looking definition. Ideal as a complement to injectable treatments or as a powerful standalone solution for daily use.

Features and Benefits:

Targets Wrinkles & Volume Loss – Helps reduce the look of expression and static wrinkles while restoring volume for a more lifted, refined appearance.
Complements Injectable Treatments – Enhances and extends the visible effects of neurotoxins and dermal fillers.
Supports Skin Structure – Strengthens the appearance of skin’s structural integrity while boosting natural hyaluronic acid for plumper, more hydrated skin.
Soothes & Protects – ZO’s exclusive ZPOLY™ complex helps reduce redness and supports the skin barrier.

Clinically Proven Results

Wrinkle Reduction – 92% of participants saw fewer visible fine lines.
Volume & Firmness – 86% experienced improvement in hollow areas and 84% noticed more defined facial geometry.
Skin Elasticity – Improvements in firmness and elasticity were seen as early as 2 weeks, with continued results at 12 weeks.
Hydration – 100% of subjects experienced improved skin hydration by week 4.

Key Ingredients

Acetyl Octapeptide-3 – A neuropeptide that softens the look of dynamic lines, especially around the eyes and forehead.
Acetyl Hexapeptide-8 – Works synergistically to smooth deeper static wrinkles and support natural collagen.
Volumizing Tripeptide – Boosts natural hyaluronic acid for fuller, plumper-looking skin.
Refining Peptide Complex – A dual-peptide blend that enhances skin structure for a sculpted, lifted appearance.

Alcohol-Free and Fragrance-Free

How to Use

Apply to clean, dry skin morning and night. Follow with your ZO daily skincare regimen for optimal results.

Ingredients

Key Ingredients:

Peptides
Antioxidants
Vitamin E
Botanical Extracts
Hyaluronic Acid (HA)

Full Ingredients:

Aqua / Water / Eau, Glycerin, Propanediol, Acetyl Octapeptide-3, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Tocopherol, Caprylyl Glycol, Hexylene Glycol, Sodium Hyaluronate, Galactoarabinan, Schizophyllan, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Beta-Sitosterol, Lecithin, Hydrogenated Phosphatidylcholine, Lysolecithin, Carbomer, Xanthan Gum, Magnesium Chloride, Disodium EDTA, Phytic Acid, Maltodextrin, Squalene, Aminomethyl Propanol, Citric Acid, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate

Ingredients may change, refer to packaging for the most current information.

Benefits & Preferences

Key Product Benefits

Firming
Elastin Boosting
Collagen Boosting
Calming
Hydrating
Moisturizing
Repairing
Rejuvenating
Fine Line Reducing
Anti-Aging

Product Preferences

Medical Grade
Paraben-Free
Fragrance-Free

Product Specs

Product Form

Serum
Gel

For Skin Types

Acne Prone Skin
Sensitive Skin
Pigmented Skin
Normal Skin
Mature Skin
Oily Skin
Congested Skin
Combination Skin
Dry Skin
All Skin Types

Application Area(s)

Face Treatments
Neck Treatments

ZO Skin Health

About ZO Skin Health

Founded by world-renowned dermatologist Dr. Zein Obagi, ZO Skin Health is a leader in medical-grade skincare, combining advanced dermatological science with innovative ingredients and clinically informed formulations. Built on the philosophy that healthy skin is the foundation of beautiful skin, ZO develops comprehensive skincare solutions designed to improve skin function, address visible signs of aging, and support long-term skin health.

From advanced retinol treatments and antioxidant serums to pigment-correcting products, growth factor technology, and daily sun protection, ZO Skin Health offers targeted solutions for a wide range of skin types and concerns.

Shop Authentic ZO Skin Health at Rejuvent

Rejuvent Skincare is an authorized ZO Skin Health retailer, offering 100% authentic products through our physician-directed skincare practice, led by Dr. Kelly Bomer, MD.

Select ZO Skin Health products are available for online purchase through our Rejuvent VIP+ program. Our team can assist with product recommendations, eligibility, and personalized skincare regimens.

Join our VIP Program now

Shop ZO Skin Health

Rejuvent Skincare

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Authentic products guaranteed
Our products are shipped directly to us from the manufacturer
Products approved by Facial Plastic Surgeon Kelly Bomer, MD

When purchasing from Rejuvent Skincare, you will always receive authentic products! Unauthorized retailers sell products that may be diluted, mixed, open and altered, expired, or counterfeit. For your personal health and safety, we recommend always purchasing your skin care products through authorized resellers like Rejuvent Skincare.

Rejuvent Skincare is owned and operated by Facial Plastic Surgeon Dr. Bomer, MD.

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5 stars: 2 (67%)
4 stars: 0 (0%)
3 stars: 1 (33%)
2 stars: 0 (0%)
1 star: 0 (0%)

1- How is your skin?: Dry

2- What is your skin's complexion?: Fair

3- How are your pores?: More Noticeable on Nose and Chin

4- How is the weather where you live?: The weather is Humid

Jury is out. I’ve not used it long enough to notice anything.

Hi Mary, thank you for sharing your honest thoughts. We hope you see some great results with continued use. Feel free to reach out if you have any questions or need advice!

1- How is your skin?: Neither Dry nor Oily

2- What is your skin's complexion?: Medium

3- How are your pores?: Small

4- How is the weather where you live?: The weather is Dry

Love this

I use this instead of Obaji and I love it.

I have been using this for a few weeks and already notice a tightness in my skin. It also makes my skin very soft and smooth.

1- How is your skin?: Neither dry nor oily
2- What is your skin's complexion?: Fair
3- How are your pores?: Small
4- How is the weather where you live?: The weather is humid

ZO Skin Health Peptide Facial Refining Concentrate Wrinkle Modulating + Plumping Serum

Dr. Bomer’s Insight

Kelly Bomer, MD

The New Science of Sculpting

Product Overview

How to Use

Ingredients

Benefits & Preferences

Product Specs

ZO Skin Health

About ZO Skin Health

Shop Authentic ZO Skin Health at Rejuvent

Rejuvent Skincare

Why can't I see all prices?

How do I earn LuxePoints?

100% Authorized Reseller

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