SkinCeuticals Advanced RGN-6

SkinCeuticals Advanced RGN-6 is an advanced regenerative cream to visibly reverse 6 signs of aging and skin tone damage. Powered by 6 core ingredients for 6 distinct dimensions of rejuvenation, Advanced RGN-6 is developed to be used both alongside laser treatment and as part of your daily routine. When paired with laser treatments, Advanced RGN-6 optimizes rejuvenation outcomes and reduces recovery time. Physician tested with laser across all skin tones.

When used as part of a daily skincare routine, Advanced RGN-6 visibily improves 6 signs of aging and skin tone damage including visible redness, post-acne marks, dark spots, wrinkles, smoothness and firmness.

Advanced RGN-6 Daily Benefits:

• Visibly reduces redness, post-acne marks, dark spots, and wrinkles
• Improves skin smoothness and firmness
• Noticeable results in as little as 1 week

Advanced RGN-6 Post-Treatment Benefits:

• Helps calm the skin and reduce downtime
• Supports skin recovery and enhances visible results

Advanced RGN-6 Features & Benefits:

• Developed for both daily use and post-treatment use
• Helps reverse visible aging damage from 1 week with daily use
• Helps strengthen the skin barrier
• Reduces visible redness, post-acne marks, dark spots, and wrinkles with daily use
• Helps reduce downtime post procedure
• Paraben-free, fragrance-free, alcohol-free
• Ideal for all skin types, even very sensitive skin

Featured Ingredients:

• 10% Glyco-Repair™ – A nutrient-rich compound derived from carob seeds, Glycorepair™ supports skin barrier repair and promotes smoother, more refined texture.
• 1% Eperuline – Sourced from the bark of the Eperua falcata tree, Eperuline helps calm the skin, diminish visible signs of aging, and protect against oxidative stress—especially following laser treatments.
• 2% Niacinamide – Also known as Vitamin B3, Niacinamide visibly improves uneven skin tone and blotchiness while reinforcing the skin’s moisture barrier.
• 3% Acetyl Tetrapeptide-9 – A potent signaling peptide, Acetyl Tetrapeptide-9 helps strengthen the skin’s structural foundation, promoting a firmer, more resilient appearance.
• 0.2% Ectoin – An extremolyte derived from amino acids, Ectoin shields the skin from oxidative stress and environmental aggressors while helping to prevent discoloration.
• 0.2% Bioceramide-603 – A patented ceramide analog, Bioceramide-603 targets post-treatment redness and pigmentation for a more even, calm complexion.

Advanced RGN-6 is a regenerative cream inspired by laser science. When used daily it helps improve signs of aging andskin tone damage. When used post-procedure, it helps optimize rejuvenation outcomes and reduce recover post-laser recovery time.

SkinCeuticals Advanced RGN-6 Clinical Study:

Proven Power — On Its Own

In a 12-week clinical study, Advanced RGN-6 demonstrated significant improvements in key signs of daily skin aging:

• 69% reduction in visible redness
• 36% reduction in post-acne marks
• 26% reduction in dark spots
• 18% reduction in wrinkles
• 35% increase in skin smoothness
• 35% increase in firmness

Study Protocol:
A 12-week clinical evaluation involving 76 female participants, ages 35–60, with Fitzpatrick skin types I–VI. The product was applied twice daily alongside a standard cleanser and sunscreen. Results were assessed at baseline and at weeks 1, 4, 8, and 12.

Enhances Post-Treatment Recovery

Advanced RGN-6 supports faster, more complete post-procedure skin recovery—visibly reducing roughness, improving hydration, and amplifying six key signs of skin rejuvenation.

Study Protocol:
A 4-week clinical study on 35 female participants, ages 30–65, with Fitzpatrick types II and III. Participants used either the test product or a control twice daily, along with a standard cleanser and sunscreen. Following a fractional laser treatment (Halo, Sciton, 1470nm, non-ablative mode), evaluations were conducted at baseline and Day 28 using clinical grading (10-point scale), self-assessments, and both objective and subjective tolerance measures.

Accelerates Healing After Laser Procedures

In a controlled, evaluator-blinded study, Advanced RGN-6 accelerated skin recovery following laser exposure:

Study Protocol:
A single-center, randomized study involving 26 male and female participants, ages 23–50, with Fitzpatrick types I–IV. Two standardized test sites were created using a Sciton Erbium:YAG laser on the forearm. One site received Advanced RGN-6 immediately post-treatment, applied twice daily thereafter; the other site was left untreated. Healing progress was monitored via clinical and bioinstrumentation assessments at baseline, immediately post-laser, and on Days 1, 7, 11, 14, and 18. Data on file at SkinCeuticals.com

Daily Application:

1. Cleanse thoroughly and apply SkinCeuticals Vitamin C antioxidant serum.
2. Dispense 1-2 pumps of Advanced RGN-6 into the palm.
3. Gently press onto the face, targeting the forehead, cheeks, and chin.
4. Follow with your favorite SkinCeuticals sunscreen in the morning.

Post-Laser Procedure Application:

1. Immediately apply Advanced RGN-6 after your laser treatment.
2. Continue applying twice daily to enhance recovery and rejuvenation.

Caution: For external use only. Avoid direct contact with the eyes.

Ingredients: – 855416 47 – aqua / water / eau, glycerin, ethyl oleate, niacinamide, squalane, C-12-16 alcohols, glyceryl stearate citrate, butyrospermum parkii butter / shea butter, maltodextrin, ammonium polyacryloyldimethyl taurate, phenoxyethanol, dimethicone, palmitic acid, hydrogenated lecithin, cetyl alcohol, ceratonia siliqua seed extract / carob seed extract, caprylyl glycol, 2-oleamido-1, 3-octadecanediol, ectoin, tocopherol, eperua falcata bark extract, xanthan gum, ethylhexylglycerin, phytic acid, adenosine, sodium hydroxide, sodium benzoate, acetyl tetrapeptide-9, citric acid,

Ingredients may change, refer to packaging for the most current information.

SkinCeuticals was born from decades of skin cancer research that led to pivotal breakthroughs in antioxidants, their high potency formulas are concentrated in active ingredients and proven to penetrate optimally into the skin. Made in the USA, this medical-grade skincare is formulated to correct signs of aging, protect healthy skin, and prevent future damage. SkinCeuticals is backed by proven science to help maintain and improve skin health. These products are only available through dermatologists, plastic surgeons, spas, and other skincare professionals.

Rejuvent Skincare sells 100% authentic SkinCeuticals products and we are authorized to sell to Rejuvent’s patients. Visit SkinCeuticals Skincare to see all products.